Shubham Raturi, Pallavi Singh, Saurabh Kumar Jha et al.

Journal of Applied and Natural Science • 2022

As the energy demand is continuously rising with the increase in population, the use of fossil fuels is also increasing at the same rate. These fossil fuels release greenhouse gases (GHG) which are harmful to human health and our environmental health and these fuels are also expected to exhaust in the near future. This eventually has led to an emerging need to shift to a more reliable, sustainable, clean energy source. Biohydrogen as fuel is a potential alternative, as hydrogen has proved to be one such fuel which has the potential to replace fossil fuels. There is a need to produce it in a clean, sustainable way to compete with the fuels that are being used currently. The hydrogen which is produced biologically is known as biohydrogen. Microorganisms also play a huge role in the process of hydrogen generation by virtue of their natural mechanism. Hydrogen can be produced biologically using approaches like biophotolysis (direct and indirect), fermentation (dark and photo) and microbial electrolysis cell (MEC). Among all, dark fermentation seems to be the most efficient when compared to other procedures. The challenges currently being faced with this technology are the yield of hydrogen, the high cost of the reactor and system efficiency. This technology still needs a lot of research and improvement to replace fossil fuels entirely.

Jianmei Luo, Xiao Li, Jingmei Zhang et al.

Biosensors and Bioelectronics • 2020

Sara Mateo, F.J. Fernández, Pablo Cañizares et al.

Electrocatalysis • 2017

Hanish Mohammed Coppath Hamza, Prabha Duraisamy, Selvendiran Periyasamy et al.

Indian Journal of Science and Technology • 2017

Objectives: Raw distillery effluent put to use as substrate for electricity generation in MFC and effectiveness in treatment including heavy metals reduction using MFC are the focus of the study. Methods/Statistical Analysis: Dual chamber fuel cells were fabricated using Poly (methyl methacrylate) sheet as a single unit, graphite rods are used as electrodes. Microporous PVC separators are used for salt bridge to distinct the anode and cathode chambers so as comparing with the conventional ‘H’ type dual chamber reactor the distance between the electrodes are reduced. The fuel cells were operated in batch mode at room temperature. Findings: The Microbial Fuel Cell is a bio-electrochemical device draws electricity from the microorganism that utilizes the organic matter from the wastewater, different wastewater could be employed as a substrate. Distillery effluent consist of high chemical oxygen demand, it effectuated electricity generation for 73 days. The fuel cells produced a maximum voltage of 206 mV that derived a maximum current density 123.50 mA/m2 and power density of 25194.8 mW/m2 . Electricity generation and effluent treatment depends on the ability of the microorganism to convert the organic matter of the substrate. The COD removal 68.7% was obtained from the fuel cell it is effective than the conventional treatment techniques without pretreatment or dilution of the effluent. The MFC treatment also assisted the removal of Nitrate 76.6%, Phosphate 79.4%, Sulphate 70.8%. The overall performance of the fuel cell determined by the Columbic Efficiency rendered by the process was 47.12%. Elemental analysis of treated effluent exhibited considerable reduction of heavy metals present in the distillery effluent. Application/Improvements: This study shows that the treatment of raw distillery effluent is effective with MFC technique. It also signifies the potential of heavy metal reduction with MFC by simultaneous electricity generation. Keywords: COD, Distillery Effluent, Electricity, Heavy metals, MFC, Treatment

Chao Li, Quan Yuan, Liangshan Hao et al.

The Science of The Total Environment • 2024

Miten Jain, Sergey Koren, Karen H. Miga et al.

Nature Biotechnology • 2018

We report the sequencing and assembly of a reference genome for the human GM12878 Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore sequencer. 91.2 Gb of sequence data, representing ∼30× theoretical coverage, were produced. Reference-based alignment enabled detection of large structural variants and epigenetic modifications. De novo assembly of nanopore reads alone yielded a contiguous assembly (NG50 ∼3 Mb). We developed a protocol to generate ultra-long reads (N50 > 100 kb, read lengths up to 882 kb). Incorporating an additional 5× coverage of these ultra-long reads more than doubled the assembly contiguity (NG50 ∼6.4 Mb). The final assembled genome was 2,867 million bases in size, covering 85.8% of the reference. Assembly accuracy, after incorporating complementary short-read sequencing data, exceeded 99.8%. Ultra-long reads enabled assembly and phasing of the 4-Mb major histocompatibility complex (MHC) locus in its entirety, measurement of telomere repeat length, and closure of gaps in the reference human genome assembly GRCh38.

Huakan Zhao, Lei Wu, Guifang Yan et al.

Signal Transduction and Targeted Therapy • 2021

Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on therapeutic outcomes. Chronic inflammation facilitates tumor progression and treatment resistance, whereas induction of acute inflammatory reactions often stimulates the maturation of dendritic cells (DCs) and antigen presentation, leading to anti-tumor immune responses. In addition, multiple signaling pathways, such as nuclear factor kappa B (NF-kB), Janus kinase/signal transducers and activators of transcription (JAK-STAT), toll-like receptor (TLR) pathways, cGAS/STING, and mitogen-activated protein kinase (MAPK); inflammatory factors, including cytokines (e.g., interleukin (IL), interferon (IFN), and tumor necrosis factor (TNF)-α), chemokines (e.g., C-C motif chemokine ligands (CCLs) and C-X-C motif chemokine ligands (CXCLs)), growth factors (e.g., vascular endothelial growth factor (VEGF), transforming growth factor (TGF)-β), and inflammasome; as well as inflammatory metabolites including prostaglandins, leukotrienes, thromboxane, and specialized proresolving mediators (SPM), have been identified as pivotal regulators of the initiation and resolution of inflammation. Nowadays, local irradiation, recombinant cytokines, neutralizing antibodies, small-molecule inhibitors, DC vaccines, oncolytic viruses, TLR agonists, and SPM have been developed to specifically modulate inflammation in cancer therapy, with some of these factors already undergoing clinical trials. Herein, we discuss the initiation and resolution of inflammation, the crosstalk between tumor development and inflammatory processes. We also highlight potential targets for harnessing inflammation in the treatment of cancer.

Timoth Mkilima, Yerkebulan Zharkenov, Лаура Утепбергенова et al.

Case Studies in Chemical and Environmental Engineering • 2023

This study explored the effectiveness of integrating Microbial Fuel Cells (MFC) with Metal-Organic Frameworks (MOF) enhanced by graphene oxide as a unique approach for carwash effluent treatment. The research encompassed three key components: analyzing MFC in isolation, evaluating MOF alone, and studying the combined MFC and MOF approach. The results demonstrated that the simultaneous use of MOF and MFC led to significant improvements in pollutant removal, indicating a synergistic effect on various pollutants within the wastewater. In retrospect, the MFC displayed low power density (0.095 mW/m2) and current density (2.8 mA/m2) during the initial 2 hours. However, a significant increase occurred, peaking at 46.2 mA/m2 and 21.62 mW/m2 by the 18th hour. Although current density decreased thereafter, power density stayed relatively high, indicating stabilization of microbial activity. The 48-h experiment concluded with 17.4 mA/m2 and 11.28 mW/m2. Notably, the combined MOF and MFC treatment consistently outperformed individual treatments, especially in the removal of heavy metals like zinc, nickel, and cadmium, with zinc removal rates increasing from 92.6 % to 96.5 %. In terms of organic contaminants, the integrated treatment approach achieved a remarkable 99.2 % removal of Biochemical Oxygen Demand (BOD). Moreover, the integrated treatment approach achieved a remarkable 100 % removal efficiency for turbidity and TSS, resulting in improved water clarity due to better fine suspended particle removal facilitated by MFC. The findings suggest that the combination of MOF and MFC holds great potential for comprehensive wastewater treatment, effectively eliminating a range of contaminants, including organic compounds, heavy metals, and general water quality parameters. The practical application of this integrated method can be further optimized and expanded through additional research and system refinement.

Min Feng, Meng Li, Zheng Zhang et al.

Electrochimica Acta • 2024

Carmen M. Fernández‐Marchante, Yeray Asensio, Luis Fernando León‐Fernandez et al.

Journal of Electroanalytical Chemistry • 2018

Fangcheng Su, Fang Wang, Changsen Zhang et al.

Journal of Cleaner Production • 2022

Kumar Sonu, Monika Sogani, Zainab Syed et al.

ChemistrySelect • 2020

Abstract This paper describes the potential of waste biomass derived biochar for improvement in the dye wastewater treatment in a microbial fuel cell (MFC). The complete MFC, an energy generating unit, was made with the waste products in order to demonstrate that low cost alternatives are available to replicate the positive results. Waste corncob derived biochar produced after acid modification has been evaluated as a supplement in an MFC for treatment of real dye wastewater (RDW). The two doses of sulfuric acid modified corncob biochar (SA‐MCB), (0.5 g and 1 g) and a blank (without any dose) were assessed for the effect on MFC performance. The maximum power density (49.92 W/m 2 ), current density (0.28 A/m 2 ), COD removal efficiency (88.39%), decolorization efficiency (81.6%) and TDS reduction (84.4%) were obtained with 0.5 g biochar dose. The Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR) analysis revealed the structural changes occurring on the SA‐MCB after use in the MFC. The SEM analysis revealed the better biofilm formation due to SA‐MCB deposition. Power density with 0.5 g of SA‐MCB dose improved to more than 24 times in comparison to the system without any such dose. The UV spectrophotometer analysis confirmed the azo bond deformation during treatment. The overall results suggest that the use of SA‐MCB biochar as anode material and as a supplement in the MFC system may provide an effective anode‐biofilm in MFCs for wastewater treatment.

Gulab Singh, S. K. Patidar

BioEnergy Research • 2020

Yiwen Yang, Ming-Jia Li, Tzu‐Chen Hung

Fuel • 2024

William Francisconi Taufemback, Dachamir Hotza, Derce de Oliveira Souza Recouvreux et al.

Materials Chemistry and Physics • 2024

N. Saniei, Nahid Ghasemi, Ali Akbar Zinatizadeh et al.

Environmental Technology & Innovation • 2021

In this work, hydrophilic nanoparticles of goethite and its derivatives with functional groups of tannic acid and sulfanilic acid were prepared. The synthesized nanocomposites were embedded into sulfonated poly ether ether ketone (SPEEK) as base polymer of proton exchange membrane (PEM) for improvement of microbial fuel cell (MFC) performance. The SEM images, FTIR and AFM tests and contact angle measurements verified hydrophilic properties of the fabricated membranes. Proton exchangeability of the fabricated PEMs was examined in a two-chamber MFC under the same operating conditions (initial COD and biomass concentration of 3300 and 1500 mg/l, respectively). The MFC performance was assessed in terms of COD removal, coulombic efficiency, power density and current density. The best result was obtained from SPEEK nanocomposite membrane with goethite 0.5% wt. The proposed PEM showed significant improvement in terms of the maximum power density (73.7 mW/m2) and current density (293 mA/m2) compared to the bare membrane. A relatively high coulombic efficiency of 52.6% with COD removal of 97.6% was achieved.

Yixuan Wang, Wenqiang Li, Wenming Zong et al.

The Science of The Total Environment • 2019

Hong Sun, Qiang Tang, Yang Li et al.

Environmental Science & Technology • 2022

Microbial extracellular electron transfer (EET) is the basis for many microbial processes involved in element geochemical recycling, bioenergy harvesting, and bioremediation, including the technique for remediating U(VI)-contaminated environments. However, the low EET rate hinders its full potential from being fulfilled. The main challenge for engineering microbial EET is the difficulty in optimizing cell resource allocation for EET investment and basic metabolism and the optimal coordination of the different EET pathways. Here, we report a novel combinatorial optimization strategy with a physiologically adapted regulatory platform. Through exploring the physiologically adapted regulatory elements, a 271.97-fold strength range, autonomous, and dynamic regulatory platform was established for Shewanella oneidensis , a prominent electrochemically active bacterium. Both direct and mediated EET pathways are modularly reconfigured and tuned at various intensities with the regulatory platform, which were further assembled combinatorically. The optimal combinations exhibit up to 16.12-, 4.51-, and 8.40-fold improvements over the control in the maximum current density (1009.2 mA/m 2 ) of microbial electrolysis cells and the voltage output (413.8 mV) and power density (229.1 mW/m 2 ) of microbial fuel cells. In addition, the optimal strains exhibited up to 6.53-fold improvement in the radionuclide U(VI) removal efficiency. This work provides an effective and feasible approach to boost microbial EET performance for environmental applications.

Bolong Liang, Yubo Zhao, Kexun Li et al.

Applied Surface Science • 2019

Song‐Jeng Huang, Aristotle T. Ubando, Chuanyun Wang et al.

Biomass and Bioenergy • 2021

V.M. Ortiz-Martínez, M.J. Salar-García, Khaled Touati et al.

Energy • 2016

Xian Cao, Chunyan Yu, Hui Wang et al.

Environmental Technology • 2016

In this study, the soil microbial fuel cells (MFCs) were constructed based on sandy soil to remove the refractory organic pesticide hexachlorobenzene (HCB) in topsoil by a simple method. The construction of membraneless single-chamber soil MFCs by setting up the cathode- and the anode-activated carbon, inoculating the sludge and adding the co-substrates can promote HCB removal significantly. The results showed that HCB removal efficiencies in the soils contaminated with 40, 80 and 200 mg/kg were 71.14%, 62.15% and 50.06%, respectively, which were 18.65%, 18.46% and 19.17% higher than the control, respectively. The electricity generation of soil MFCs in different HCB concentrations was analyzed. The highest power density reached was 70.8 mW/m 2 , and an internal resistance of approximately 960 Ω was obtained when an external resistance loading of 1000 Ω was connected. Meanwhile, the influences of temperature, substrate species and substrate concentrations on soil MFCs initial electricity production were investigated. The addition of the anionic surfactant sodium dodecyl sulfate (SDS) into the soil MFCs system contributed to the improvement in HCB removal efficiency.

Wenwen Tan, Zhengxin Yang, Qi Feng et al.

Journal of Power Sources • 2023

Demin Jiang, Hao Xie, Huina Chen et al.

International Journal of Hydrogen Energy • 2022

Abdullah Al-Mamun, Tahereh Jafary, Mahad Baawain et al.

Environmental Research • 2020

I.M. Rizwanul Fattah, Jahangir Alom, Jahid Uz Zaman et al.

Journal of Power Sources • 2024

Microbial fuel cells (MFCs) represent a promising renewable energy source, harnessing the metabolic processes of microorganisms to generate electricity through substrate oxidation. Hydrogels have recently garnered significant attention for their potential to enhance MFC performance and efficiency by addressing critical challenges associated with electrode materials, proton exchange membranes, microbial immobilization, and overall system stability. This review comprehensively explores the latest advancements in hydrogel-based approaches for MFC applications. The article begins with the unique properties of hydrogels related to fuel cells, including their biocompatibility, porosity, ionic transport capability, and tunable physicochemical properties, which make them ideal candidates for MFC applications. Moreover, the review discusses diverse methodologies for incorporating hydrogels into MFCs, including electrode modification, microbial consortium immobilization matrices, and separators. Research findings indicate that incorporating conductive elements into hydrogels or fabricating hybrid hydrogel-based anodes has led to notable improvements in electrical conductivity and power density output. However, further research is imperative to enhance power generation efficiency, long-term stability, and scalable preparation for sustainable MFC operation. This review concludes by discussing the challenges and opportunities associated with the use of hydrogels in MFCs.

Ahmed Y. Radeef, Zainab Z. Ismail

Separation and Purification Technology • 2022

Geetanjali Geetanjali, Simran Kaur Dhillon, Patit Paban Kundu

Journal of Power Sources • 2022

Junfeng Chen, Jiaqi Yang, Yongyue Zhao et al.

International Journal of Hydrogen Energy • 2023

Hongbo Liu, Feiyu Ouyang, Zihua Chen et al.

The Science of The Total Environment • 2020

Xiaoling Zhang, Xinxin Miao, Jiandi Li et al.

Chemical Engineering Journal • 2018

Marta Fernández-Gatell, Clara Corbella, Xavier Sánchez‐Vila et al.

Chemosphere • 2021

Siyu Zhang, Xinpeng Zhao, Xinqi Guo et al.

Chemical Engineering Journal • 2023

Juping You, Jian Yu, Shihan Zhang et al.

Chemical Engineering Journal • 2022

D. Vidhyeswari, A. Surendhar, S. Bhuvaneshwari

Chemosphere • 2022

Yuanfeng Liu, Xiuling Zhang, Huiyu Li et al.

Electrochimica Acta • 2021

Peter Lindblad, David Fuente, Friederike Borbe et al.

Algal Research • 2019

CyanoFactory, Design, construction and demonstration of solar biofuel production using novel (photo)synthetic cell factories, was an R&D project developed in response to the European Commission FP7-ENERGY-2012-1 call “Future Emerging Technologies” and the need for significant advances in both new science and technologies to convert solar energy into a fuel. CyanoFactory was an example of “purpose driven” research and development with identified scientific goals and creation of new technologies. The present overview highlights significant outcomes of the project, three years after its successful completion. The scientific progress of CyanoFactory involved: (i) development of a ToolBox for cyanobacterial synthetic biology; (ii) construction of DataWarehouse/Bioinformatics web-based capacities and functions; (iii) improvement of chassis growth, functionality and robustness; (iv) introduction of custom designed genetic constructs into cyanobacteria, (v) improvement of photosynthetic efficiency towards hydrogen production; (vi) biosafety mechanisms; (vii) analyses of the designed cyanobacterial cells to identify bottlenecks with suggestions on further improvements; (viii) metabolic modelling of engineered cells; (ix) development of an efficient laboratory scale photobioreactor unit; and (x) the assembly and experimental performance assessment of a larger (1350 L) outdoor flat panel photobioreactor system during two seasons. CyanoFactory - Custom design and purpose construction of microbial cells for the production of desired products using synthetic biology – aimed to go beyond conventional paths to pursue innovative and high impact goals. CyanoFactory brought together ten leading European partners (universities, research organizations and enterprises) with a common goal – to develop the future technologies in Synthetic biology and Advanced photobioreactors.

Xiayuan Wu, Zixuan Chen, Zuopeng Lv et al.

Journal of Cleaner Production • 2021

Seyed Alireza Mousavi Rabeti, Mohammad Hasan Khoshgoftar Manesh, Majid Amidpour

Journal of Cleaner Production • 2023

Hafiz Muhammad Adeel Sharif, Muhammad Farooq, I. Hussain et al.

Journal of the Taiwan Institute of Chemical Engineers • 2021